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  • E CHUNG MACHINERY CO.

  • Multiple-Effect Distillation (WFI)

  • Multiple-Effect Distillation (WFI)

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    1. Automatic Ultrasonic Washing Machine 320℃ (For Vial & Ampoule) ERVW-01

    2. Tunnel Drying Sterilizer and Depyrogenation 320℃ (Class 100 Type) ETS-01

    1. Steam Sterilizer (Autoclave) APSR-01

    2. Superheated Water Sterilizer (Autoclave) APWR-01

    3. Steam-Air Mixture Sterilizer (Autoclave) APST

    1. Hot Air Sterilizer (Class 100 Type) ECHS-01

    2. Vacuum Permeameter (76cmHg) VP-010

    1. Pure Water System Equipment (RO+EDI) ECPW-700

    1. Multiple-Effect Distillation (WFI) MS-01

    1. Pure Steam Generator ECSG-01

    1. Sterile Mixing Tank (Magnetic Stirring . Load Cell)

    2. Sanitary Mixing Tank

    3. Distilled Water Storage Tank

    1. Through Circulation Dryer TCD-150

    2. Vacuum Permeameter (76cmHg) VP-010

    1. Hot Air Circulation Oven (100°C ~ 500°C) HMO-010

    2. Hot Air Circulation Oven (300 ℃) AM-300

    3. Clean Room Oven 300℃ (Class 100 Type) CR-010

    4. Vacuum Oven VO-010

    5. Inert Gas Oven

    6. Pressure Oven / Vacuum Oven

    7. Vacuum Permeameter (76cmHg) VP-010

    8. Continuous Feeding I.R. Oven IR-010

    9. Continuous UV Curing Machine UV-010

    1. Automatic Ampul & Vial Washing Machines Tray Type ECVW-100

    2. Automatic Bottle Washing Machine (Rotary Type)

    3. Rotary Washing Machine ECRW-01

    1. Salt Spray Tester

    2. Air To Air Thermal Shock Test Chamber (-65℃ ~ +150℃)

    3. Temp. and Humidity Chamber (-60℃ ~ 200℃)

    4. Hot Air Circulation Oven AM-010

    5. Hot Air Conveyor Oven ACO-010

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Dryer Equipment / Injection Filling Machine / Medicine Filling Machine / Pharmanceutical Machinery  - Echung Machinery Co.
E CHUNG MACHINERY CO.

E CHUNG MACHINERY CO. is Professional manufacturer of CGMP PHARMACEUTICAL BIOTECH FOOD-MARKING EQUIPMENT,INDUSTRIAL-USE, HEATING & DRYING EQUIPMENT.

  • Products
    1. All Category

    2. PIC/S GMP & cGMP Pharmaceutical / Biotech Industry Equipment

    3. INDUSTRIAL-USE, HEATING & DRYING EQUIPMENT

    4. Oven

    5. Dryer

    6. Sterile Mixing Tank (Magnetic Stirring . Load Cell)

    7. Purre Steam Generator

    8. Multiple-Effect Distillation (WFI)

    9. Pure Water System (RO+EDI)

    10. Hot Air Sterilizer (Class 100)

    11. Autoclave Steam Sterilizer

    12. Automatic Washing Machine & Tunnel Drying Sterililzer

  • About Us
  • Inquiry
  • Video

MS-01 Multiple-Effect Distillation (WFI)

MS-01 Multiple-Effect Distillation
MS-01 Multiple-Effect Distillation
  • Overview

    Multiple-Effect Distillation (WFI) is designed to comply with the specifications of U.S. Pharmacopeia (USP) Water For Injection (WFI), and in accordance with the water quality of the supplied water source. When the temperature exceeds 80°C, the purification of water quality will be transferred in two phases.

     

    Changing to vapor from liquid, then changing to liquid from vapor. The feed water evaporates through the heat exchanger in the evaporator, and uses its latent heat to let the evaporation process through a series of 180 degree rotations by a centrifugal cyclone baffle plate device inside the separator. Forcing the particles and water drops out by the power of flow to make the vapor that leaving the baffle plate will not contain dissolved solids and pyrogens. The particles and water drops will fall to the bottom and be heated again, condensing the purified water vapor to required distilled water by condensation transferring, using a three-way valve to discharge the unqualified purity water to ensure the water quality of distilled water, and storing in a storage tank for injection pharmaceutical use.

  • Application

    • For Pharmaceutical.
  • Features

    • Water quality monitoring system.
    • The product is more energy-saving than traditional single-effect type.
    • Using double-tube plates design to prevent cross-contamination.
    • Using double-tube plates for cooling system to prevent cross-contamination.
    • Using double-tube plates for the first effect of evaporator to prevent cross-contamination.
    • Each evaporator has a window to observe the internal situation of the evaporator.
    • The heat-transfer tube’s expansion technology construction has good heat transfer efficiency and can be repaired and maintained.
    • The internal design of the heat-transfer tube is using the temperature differences to make internal circulation, which improving the efficiency of temperature rising.
    • The heat-transfer tube design of the heat exchanger improves the efficiency and achieves the energy-saving effect.
    • Using the latest design for the steam-water separated baffle of evaporator to reduce endotoxins in the water effectively.
  • Construction & Structure

    • The equipment materials that connected to the water inlet are all using stainless steel SS316L, frosted and polished 320 ~ 400#.
    • Double-tube plate design, using distillation method to treat the contaminated cooling water through the glass fiber.
    • The external materials and flanges of the equipment are all using SS304.
    • The pipes are passivated before actual operation.
    • Double tube plate design. By using distillation method to treat contaminated cooling water through glass fiber.
    • The external materials and flanges of the equipment are using SS304.
    • The pipes are passivated before starting actual production.
  • Processing Map

    Processing Map

  • Process

    The equipment is using the working principle of heat exchanger, the first cylinder is heated by external steam, other cylinders are heated by the first cylinder's pure steam to next cylinder. Using evaporator and condenser to force the water to proceed twice variations. Details are described as follows:

    First of all, letting the feed water that inside evaporator to pass through heat exchanger, the liquid will be changed to gaseous, then using its latent heat to get into separator. There's a special mist damper and a high centrifugal force cyclone device inside the separator, the steam will pass through 180 degree continuous rotation and separate particles, drops and pyrogen when passing through the special device that mentioned above. The steam that leaves separator is sterile and does not contain solution solid and pyrogen. The particles and drops will return to the bottom of evaporator cylinder and be heated again, only the high-speed purified steam can pass through the separator and get into condenser at this stage.

    After that, proceeding the second variation, the steam that inside condenser will be changed to liquid (distillate) from steam by passing through cooling exchanger, and using diverter valve to ensure the quality of distilled water. If the water quality is lower than the purity setting, then it will be discharged to drainage pipe, otherwise, it will be flown to storage tank to provide for the purpose of pharmaceutical Water For Injection (WFI).

    In addition, due to the fact that it adopts multiple effect type, it will be preheated by the first condenser before injecting water to each cylinder, meanwhile, the evaporation that inside feed water latent heat piping device for each cylinder is equipped with recovery device to save the consumption of steam energy.

  • Specification

    Model Number of Effects 5 Bar Steam Heating Dimensions
    Production Capacity (Lt/hr) Steam (kg/hr) Cooling Water (Lt/hr) Height (mm) Length (mm) Width (mm) Weight (mm)
    MS-250/4 4 250 85 280 2500 1300 700 800
    MS-500/4 4 510 150 500 2500 1300 900 900
    MS-500/5 5 510 130 300 2500 1450 900 1000
    MS-1000/5 5 1200 320 600 2900 1900 1000 2000
    MS-1000/6 6 1200 270 600 2900 2240 1000 2300
    MS-1500/5 5 1700 420 750 3200 3040 1050 2700
    MS-1500/6 6 1700 350 750 3200 3350 1050 3000
    MS-2000/5 5 2200 620 1000 3200 3000 1100 3300
    MS-2000/6 6 2200 550 1000 3200 3430 1100 3800
    MS-3000/6 6 3200 700 1200 3700 3900 1300 4800
    MS-4000/6 6 4300 1000 1400 3900 4480 1400 6800

    ※ We can accept customer specify specification.

  • Tags

    #Distillation #Multiple Effect Type Stills #Multiple-Effect Distillation
Dryer Equipment / Injection Filling Machine / Medicine Filling Machine / Pharmanceutical Machinery  - Echung Machinery Co.
E CHUNG MACHINERY CO.

E CHUNG MACHINERY CO. is Professional manufacturer of CGMP PHARMACEUTICAL BIOTECH FOOD-MARKING EQUIPMENT,INDUSTRIAL-USE, HEATING & DRYING EQUIPMENT.

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